نتایج جستجو برای: Sodium channels

تعداد نتایج: 317357  

Journal: :Brain and Neuroscience Advances 2018

Journal: :iranian j. of fisheries science 2016
a mostafaeipour

aquaculture is among the oldest occupations of human being. over the past quarter of century, the aquaculture industry has grown rapidly. the effect of water containing sodium sulfate on long term compressive strength of concrete of fishing ponds and channels is investigated in this paper. aim of this paper was to analyze the strength of concrete channels and of aquaculture which are in direct ...

Buthotus schach is one of the dangers scorpion in Iran that belong to the Buthidae family. Toxins are existing in venom scorpion, modulate the ion channels by blocking or opening the pore of the channel or by altering the voltage gating and useful as pharmacological tools. In the present study, we investigated the effect of venom and its obtained fractions by gel filtrations on electrophysiolog...

Journal: :iranian journal of pharmaceutical sciences 0
akram aboutorabi student research committee nima naderi department of toxicology and pharmacology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran hamid gholamipour pourbadiee department of physiology and pharmacology, pasteur institute of iran, tehran, iran. hossein zolfagharian department of venomous animals and antivenom production, razi vaccine and serum research institute, karaj, iran. hossein vatanpour department of toxicology and pharmacology, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran

buthotus schach is one of the dangers scorpion in iran that belong to the buthidae family. toxins are existing in venom scorpion, modulate the ion channels by blocking or opening the pore of the channel or by altering the voltage gating and useful as pharmacological tools. in the present study, we investigated the effect of venom and its obtained fractions by gel filtrations on electrophysiolog...

Journal: :Proceedings of the National Academy of Sciences 1999

Journal: :The Journal of pharmacology and experimental therapeutics 1997
J H Song C S Huang K Nagata J Z Yeh T Narahashi

The effects of riluzole, a neuroprotective drug, on tetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-R) sodium channels in rat dorsal root ganglion neurons were studied using the whole-cell patch clamp technique. At the resting potential, riluzole preferentially blocked TTX-S sodium channels, whereas at more negative potentials, it blocked both types of sodium channels almost equa...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1993
E H Joe K J Angelides

In myelinated axons, voltage-dependent sodium channels are segregated at high density at nodes of Ranvier (Rosenbluth, 1976; Waxman and Quick, 1978; Black et al., 1990; Elmer et al., 1990), a distribution that is critical for the saltatory conduction of action potentials (Huxley and Stampfli, 1949). The factors that specifically control the organization and immobilization of sodium channels at ...

Journal: :Brain research 2000
J Song Y Y Jang Y K Shin M Y Lee C Lee

The effects of thimerosal, a sulfhydryl oxidizing agent, on tetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-R) sodium channels in rat dorsal root ganglion neurons were studied using the whole-cell patch clamp technique. Thimerosal blocked the two types of sodium channels in a dose-dependent manner. The inhibitory effect of thimerosal was much more pronounced in TTX-R sodium chann...

Journal: :European journal of anaesthesiology 2003
H C Wartenberg J P Wartenberg B W Urban

BACKGROUND AND OBJECTIVE To investigate the effects of barbiturates on batrachotoxin-modified sodium channels from different regions of the human heart. Single sodium channels from human atria were studied and compared with existing data from the human ventricle and from the central nervous system. METHODS Sodium channels from preparations of human atrial muscle were incorporated into planar ...

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